Andrology Neurourological Rehabilitative Medicine

1) Afferent Nerve Stimulation:

Afferent Nerve Stimulation (ANS)  is a penile vibratory stimulation (PVS) methodology. It is currently the leading rehabilitative physiotherapeutic treatment today for the greater population of men in  the treatment of erectile dysfunction and ejaculatory disorders.

(Its competitor LL-ESWT is a Lithotripsy proceedure originally designed to disolve kidney stones and calcium oxalate stones . ESWT is therefore utilized specifically for disolving penile Arterial plaque in patient popultions with Artery disease.  It is not suitable for the greater popultion of men. Both Treatments ANS/PVS & LL-ESWT work by accelerating the blood flow in the Pudendal (dorsal) artery of the penis, a major source of blood for erectile tissue; & both treatments work on the premise of applied Acoustic Sound Waves.)

The (afferent) pudendal nerve  is a peripheral nerve of the somatic nervous system which carries nerve signal towards the central nervous system – the CNS receives the signal and coordinates the activity, and efferent nerve fibers relay motor commands to stimulate penile muscle contraction.

Afferent Nerve Stimulation treatment increases the endogenous production of Nitric Oxide (NO) . NO inhibits platelet aggregation, and adhesion, and modulates smooth muscle cell proliferation, improving tumescence and rigidity. Afferent nerve stimulation helps to maintain an erection of adequate strength for an adequate length of time for a functional recovery.

Patients demonstrate an average 18-31% increased peak systolic velocity compared to ICI, with 90% tumescence and 60-70% rigidity (p=0.02) and 72% in the restoration of ejaculatory function.

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1A) Post Surgical Prostatectomy Recovery.

For patients experiencing erectile dysfunction following radical prostatectomy surgery.

Afferent Nerve Stimulation is a rehabilitative treatment that promotes Neuroregeneration as the regrowth or repair of nervous tissue. Such mechanisms include regeneration of new neurons, glia, myelin and in post prostatectomy the regeneration of the nerve axons, in order to reach the synapses for appropriate neurotransmission.

Post surgical Rehabilitation activates S3 and S4 nerve roots ;including CIII, VII, IX, X, XI   promoting Autonomic balance. (The Canaverous Nerve is Autonomic.)

Erectile Dysfunction post surgical Prostatectomy is related to axonotmesis (sensory and motor loss) and impairment of the cavernous nerve that travels along the prostate. Pro-erectile afferent nerve stimulus is vital for replenishment of corporal oxygen supply and other metabolic needs. Surgical injury to the neurovascular bundles after prostate surgery suffer from a continued cycle of smooth muscle cell death leading to Veno-Occlusive Disease and often long term ED after radical surgery. Men with preserved neurovascular bundles may also have neuropraxia (progressive fibrosis of the cavernosal tissue) causing Venous leakage. Afferent stimulation helps to decrease the fibrotic changes.  Afferent nerve stimulation is a rehabilitative therapy also providing Muscle Fiber Stimulation in the process which is necessary post prostatectomy to prevent long-term penile muscle atrophy.

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2) Pelvic Floor Therapy (PFT)

Pelvic Floor Therapy is a Prostatic Therapy that utilizes intra-cavity stimulation to the pelvic floor, primarily stimulating the release of various toxins and mucoproteins from the cowpers gland, located at the base of the prostate gland. Mucoprotein in pre-ejaculate does not contain sperm cells. Regular  PFT treatments assist in maintaining pelvic and prostate health reducing the risk of prostate cancer.

Pelvic Floor Therapy may also be combined with Neurofeedback for reducing the inflammatory stress response.

Neuromodulation promotes the relaxation response of the parasympathetic nervous system enhancing relaxation and receptability in the transmission of stimuli in Pelvic Floor Physiotherapy.

2A) PEMF Pelvic Floor Therapy: ( 1-50 Hz) Indications: Precancerous Prostate Adenoma,  Chronic Prostatitis,  Inflammation.

PEMF emits intra-cavity very low frequency PEMF pulsed energy waves in the range of 1–50 Hz  – identified as a weak non-thermal electromagnetic field therapy.

It is combined with released pulses and acupressure from the perineum at various points along the front wall of the rectum to the ampulla of vas deferens above the prostate.

PEMF has a positive effect on vascularization and  the hemodynamics of the prostate  and tissues in general; reducing tissue hypoxia that was caused from abnormal blood flow patterns. PEMF improves oxygen delivery and reduces inflammation.

2B) Non-Electric Thermogenic Pelvic Floor Therapy:

The intra-cavity applicator probe is covered in Ebonite which naturally produces surface heat. Generated in the process is a natural mild electrical charge. Ebonite is an organic polymer that consists of hydrocarbon chains bonded together with low-level sulfur atoms. This allows the probe to better conform to the body’s intracavity structure. Temperature of the tissue’s surface increases as a result of the energy released.  The natural bioelectrostatic charge accumulates and causes a weak electromagnetic field. Static electricity is an imbalance of electric charges within or on the surface of tissue. The charge remains until it naturally move away by means of electrical discharge. Static electricity is named in contrast with current electricity.

Conductivity increases intra-cavity temperature thereby decreasing the sensation of fullness and pain and the thermogenic properties helps in preventing infections. For conditions such as Asymptomatic Inflammatory Prostatitis, Vasculitis, and Benign Prostate Hyperplasia- Age associated prostate gland enlargement.

Transrectal thermotherapy, where heat is applied to the prostate and pelvic muscle area, is admistered on its own singular,  or combined with medicinal therapy: this has also shown benefit with a decrese of symptoms in CP/CPPS.

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2C) Prostate Screening:

Prostate Cancer can be prevented as corrected particularly when the degenerate tissues has not yet exceeded the boundaries of the organs and there is no metastases.

Since complaints usually only occur when the disease is advanced, a Screening Examination for prostate abnormalities is available ;  and routeinly performed for patients receiving Maintenance Pelvic Floor Therapy.

Adenosis of the prostatic gland is believed to precede the development of prostate adenocarcinoma, the most common form of prostate cancer which is detectable upon Prostate Examination.

2D) Point of Care Test for Bacterial Prostatitis.
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3) Peripheral nerve stimulation 2.5 mm and 100 Hz in Neurogenic Bladder.

Using sound frequency and amplitude strengthens the external urethral sphincter.  Peripheral nerve stimulation reduces symptoms of Stress Urinary Incontinence, Post voiding Dribble and Nocturia  (frequent voiding at night). A neurogenic bladder may be independent or a related  symptom accompanying Benign Prostate Hyperplasia.

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4) Bladder Irrigation in Bacterial Prostatitis:

Acute bacterial chronic prostatitis often contains uropathogens. Chronic bacterial prostatitis is a subacute infection, that may be present with a variety of pelvic pain symptoms and neurogenic bladder voiding symptoms. Seminal vesiculitis , most often is due to bacterial infection.

Intravesical dimethyl sulfoxide is used to cleanse the bladder and to prevent bacterial transference to the kidneys.

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5) Infrared Hyperthermia for PCOS: For mobilizing BPA and phthalates .

PCOS is a multisystem disorder affecting women, caused by environmental and epigeneic impacts distinct of excessive Androgen production. Hyper-insulinemia is a contributive factor to abnormalities seen in the Hypothalamic-Pituitary-Ovarian Axis, often with Obesity, Oligo-ovulation and/or Anovulation, Infertility, with 15% of women developing Ovarian Cysts.

Concurrent with Hyperthermia for PCOS is best facilitated with the addition of holistic chelation and binding compounds : Recommendations include Lifestyle Changes such as Avoidance of Phthalates, Pesticides, and Bisphenol-A (BPA). These three groups of chemicals are implicated in endocrine disruption. Primarily Bisphenol A  exposure leads to endocrine disorders followed by morphological and functional changes in the ovary, uterus, vaginal, and oviducts. Phthalate exposure has been directly linked to Polycystic Ovary Disease, including birth defects and early or delayed puberty to name a few. Phthalates or phthalate esters are esters of phthalic acid mainly used as plasticizers. Including DEHP and MEHP.

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5A) Regional Hyperthermia for Men with PCOS-like symptoms: For mobilizing  BPA and phthalates from the tissue.

High levels of phthalates also affect Men – resulting in Endocrine disruption with high levels of estrogen,  insulin resistence, changes in the testis with a decrease in weight with atrophy of the seminiferous tubules, low sperm count, and the progressive degeneration of germ cells, Sertoli cell dysfunction and hormonal disruption in Leydig cells. Hyperthermia is facilitated for men and may be utilized with the addition of natural oral chelators and binding compounds.

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5B)  Neurofeedback :Assisting in modifying estrogen’s tendency to stimulate cortisol-binding globulin; and cell growth in Prostate Enlargement and in hormone related Cancers.

Through specific binding sites for 125I-labeled melatonin in benign prostate tissue is localized in the microsomal fraction of the glandular epithelium, showing growth inhibitory effects on the prostate.

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5C)  Neurofeedback for Hypoprolactinemia..4–7 Hz

Hypo-prolactinemia is a cause of premature ejaculation. Normal sperm characteristics can be restored when prolactin levels are brought up to normal values in men.

Neurofeedback treatment can also be utilized for emotional regulation;  CES for ammending anxiety; These are two viable Treatments. Treatment for urinary frequency may be recommended as a pathology of the kidney which may be interfering with ejaculatory measures. Afferent treatment  for urinary frequency regulates the autonomic system which sends signals to the RVS brainstem  involved in the expression of cardiovascular and respiratory changes that occur following sympthetic activation. The nPGi is one of two major afferents of the LC sending collateral projections to the NTS. These neurons have distributions to brain areas controlling autonomic activity. Hypoprolactinemia may be distinctive of autoimmune disorders. (Also Refer to 7 )

Neurofeedback for Hypoprolactinemia in men and women :

Indicative of 3 µg/L in women, and 5 µg/L in men. In women low prolactin levels are atypical of ovarian dysfunction.

Neurofeedback (0.5–4 hz) stimulates the release of several hormones, including growth hormone releasing hormone GHRH and Prolactin (PRL).

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6)  Gandharva hasta moola ( Ricinus Communis) under Low Heat : For gastrointestinal disorders that interrupt reproductive and sexual functioning in men. Also utilized as a protocol for reducing  inflammation, cysts, tumors, non-malignant and malignant adeno carcinomas in men nd women.

The Application of Gandharva Oil is facilitated and can be demonstrative for extended self-application by the patient at home.

Ricinus Constitutes: DPPH (1,1-diphenyl-2- picrylhydrazyl, Gallic acid, quercetin, gentisic acid, rutin, epicatechin and ellagic acid are the major phenolic compounds responsible for its antioxidant activity.. Gandharva  includes Barley, Gubger and Ksheera ( Milk) properties for a strong healing effect.

Adenomatous polyps, or adenomas, polyps that grow on the lining of the colon carry a high risk of colon cancer. Adenomas constitute approximately 10% of digestive polyps as cell masses forme on the stomach’s inner lining.

Cysts of parenchyma can affect the prostate due to obstruction of the glandular ductules, causing retention of prostatic secretions and dilatation of the acini.

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7) Phonophoresis:  with Glutamic Acid Decarboxylase: In Premature Ejaculatory Disorders:

Phonophoresis uses sound waves for natural medicine delivery into the tissue. The maximum energy absorption in soft tissue occurs from 2 to 5 cm. (About 2″) Intensity decreases as the sound waves penetrate deeper.

This acts in the nerve synapses junctions between nerve cells transmitting and receiving electrochemical signals to modulate the electrochemical activities between these cells. A weakness in the GAD enzyme creates an increased amount of Glutamate. Glutamate is the most abundant excitatory neurotransmitter in the vertebrate. The inhibitory neurotransmission has a positive effect  providing neuromuscular relaxation of the penile corpus.

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8) Iontophoresis for Peyronies:

Iontophoresis with sodium chloride is prescribed as a time-release system, providing slow release complete in 4 or 14 hours. It is prescribed with education for self administration at home, for dissolving Penile fibrosis.

To include the  dried flowers of C. officinalis Linn.  for use inbetween applications for its antipyretic, anti-tumor and cicatrizing effect. It promotes faster healing, soothes and  prevents infection.

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9) Holistic Contraceptive Therapy  – Consultations for Women – A grass roots approach to contraception. Complied within the Lunar Cycle.

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The information provided on this website is provided for research, educational, and informational purposes only. It is not intended to replace personal professional medical advice.

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